Amyloid precursor protein (APP) is a type I transmembrane glycoprotein that undergoes complex routing through the secretory and endocytic pathways of neurons and non-neuronal cells. Proteolytic ...

Amyloid precursor proteins (APPs) are evolutionarily conserved membrane glycoproteins that undergo complex proteolytic processing to yield fragments with diverse biological activities. Beyond their ...

Share on Pinterest New research looks into the role of amyloid-beta in developing Alzheimer’s. Westend61/Getty Images A main theory behind the cause of Alzheimer’s disease is the build-up of the ...

(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...

At the end of last month, a scientific journal pulled a research paper on Alzheimer’s disease. The retraction came from Neurobiology of Aging, which removed a 2011 paper claiming to show that a ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...